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A Crack in Creation by Jennifer Doudna & Samuel Sternberg
The New Power to Control Evolution
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For a long time I have question the central dogma of Molecular Biology & Evolution. Can it just be DNA Replication, Transcription and Translation, coupled with Random Mutation that can account for all of life and it’s diversity?
Are we just expressions of a Genetic Machine?
I vacillate continuously between believing in this dogma and entertaining more spiritual beliefs. There’s not much I can do about it. My mind says on thing, my heart (based on some wild experiences) say something else.
You can buy the book here.
Understanding CRISPR-cas9 and Other Ideas in Genetics
- Get a short ebook on CRISPR-cas9 here.
- Homologous Recombination.
- synthetic genes
- Gene Editing
Chromothripsis
Chromothripsis is the phenomenon by which up to thousands of clustered chromosomal rearrangements occur in a single event in localised and confined genomic regions in one or a few chromosomes, and is known to be involved in both cancer and congenital diseases. It occurs through one massive genomic rearrangement during a single catastrophic event in the cell’s history. It is believed that for the cell to be able to withstand such a destructive event, the occurrence of such an event must be the upper limit of what a cell can tolerate and survive.[1] The chromothripsis phenomenon opposes the conventional theory that cancer is the gradual acquisition of genomic rearrangements and somatic mutations over time.[2]
Dna replication transcription and translation
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